Unique among all cell types, the brain’s constituent cells, neurons, need to communicate with one another in intricate networks that are responsible for circuit function, and most of this communication is enabled by molecules that are released by neurons and sensed by target cells. Better understanding of chemical neuronal communication requires technologies that can help us visualize and measure the spatial and temporal dynamics of these chemical cues. Our lab is interested in developing optical biosensors that have quantal detection capabilities, high spatial resolution, and excellent signal-to-noise ratio.
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