Organogenesis in a model system: Formation of the Drosophila salivary gland and trachea

Telomere and Telomerase-Associated Disorders

In-vivo biosensing, personalized drug therapy, molecular diagnostics

Molecular Mechanisms of Neuronal Plasticity

Mechanisms of Human Movement Disorders

Computational regulatory genomics

Synaptic Physiology: Glutamate Transporters and Glial Involvement in Neuronal Signaling

Functional Organization of Local Circuits of the Neocortex

Computational and experimental exploration of gene regulatory networks in development, stem cell engineering, tumorigenesis and cancer progression

Preclinical models of neurological and psychiatric disorders

TRP channel function in thermosensation, pain and inflammation

Computer vision, pattern recognition, machine learning, artificial intelligence, signal and image processing

Decision-making, neuroeconomics, neural control of movement, functional brain imaging, noninvasive brain stimulation

Mitochondrial phospholipid metabolism in health and disease

Molecular Pathogenesis and Latency of SIV & HIV

Mass spectrometry strategies to characterize proteins and their modifications in malnutrition, neurological diseases and cancer

Messenger RNA Translation and Stability

Object Synthesis in Higher Level Visual Cortex

Cystic Fibrosis, Genetics, Medical Genetics

Genetic analysis of chemotaxis eukaryotic cells

Hair cell regeneration; Hearing; Auditory development

Circuit and Synaptic Mechanisms of Social Cognition in Health and Disease

Molecular and Genetic Studies on Pain-Sensing Neurons

Stem cells; Regenerative medicine; Biomaterials; Cornea repair; Biomaterials and stem cells for tissue engineering; Cartilage regeneration; Stem cell research; Regenerating tissue

Cellular regulation of cholesterol homeostasis and adaptation to hypoxia

Mechanisms driving growth and development of normal epithelial cells; Cellular strategies driving cancer invasion and metastasis; Regulation of cancer progression by the tumor microenvironment

Neural Basis of Multisensory Perception and Decision Making

biology, drug delivery, bacterial isoprenoid and vitamin and biosynthesis, design of anti-infective strategies

NMR studies of active enzymatic systems: dynamic molecular communication in Nonribosomal Peptide Synthetases

Zinc transporters: biochemistry, biophysics and cell biology

Cardiovascular disease; Cancer; Pathology; Toxicology; Signal transduction; Cancer therapy

Single Cell Variation in Neural Development and Disease

Engineering functional craniofacial and orthopaedic constructs for use in therapeutic applications

Developing biomaterials; stem cells; nanobiotechnology to meet challenges in regenerative medicine; ophthalmology; cancer

Mechanisms of Ribosome Translation and Translational Control

Genetic disorders associated with defective fluid and electrolyte movement; ion channel and epithelial transport physiology

Mechanisms of peripheral neuropathies; developing treatments for nerve regeneration and neuroprotection

Molecular mechanisms underlying accurate chromosome segregation and centrosome duplication

Regulation of Neurotransmitter Receptors and Brain Function in Health and Disease

Lipid Signaling in Chemotaxis

Behavioral and neurobiological mechanisms underlying adaptive and maladaptive associative learning

Systems neuroscience, brain development, in vivo imaging, neuroengineering, neurophysiology

Mechanisms of Cortical Modification

Neurophysiology of Memory in the Hippocampal Formation

Regulatory pathways that control adaptive metabolic responses in adipose and skeletal muscle tissues

CELLULAR PRINCIPLES UNDERLYING LEARNING AND COGNITION

Mechanisms of Brain Cancer Stem Cell Regulation

Receptor-ligand interactions and conformational transitions using computational and experimental approaches

Laboratory of Poly(ADP-ribose) in RNA Biology

Cellular Dynamics in space, time, and adaptation

Medical imaging and biophotonics

Neuronal Plasticity, Broadly Considered

Translational medicine; Molecular and cellular biology; Chemical biology

Proteomics; Animal models for Wilson disease, Menkes disease; Redox biology; Metal biology (copper, iron, zinc); Ion transport; Membrane proteins biochemistry; trafficking assembly regulation

Host-microbe Interactions, Microbiota, Bacterial Influences on Host Lipids and Neurotransmitters

Computational modeling of growth factor-receptor networks, personalized medicine, therapeutic cardiovascular remodeling, novel methods for data visualization and automated image analysis

Signals Regulating Stem Cell Self-renewal

Genetics basis of congenital malformations; Genetics of neurological, neuropsychiatric and neural-crest disorders; Transcriptional regulation in development and disease

The Regulation of Neuronal Gene Expression in Health and Disease

Data science, computational neuroscience, medical imaging, computational anatomy, pattern theory

Molecular mechanisms of CRISPR-Cas Immunity

Auditory Perception and Development of Neocortical Circuits

Molecular mechanisms of retinal development and disease; the role of Frizzled receptors in mammalian development

Neural Circuits Underlying Object Recognition

Neural Circuits for Touch Perception

Molecular dissection of host-pathogen interactions and the evolution of virulence strategies in natural reservoirs

Sequence motif finding; Splice site prediction; Computational gene finding

Mechanisms of signal transduction in immunity and cancer; antigen receptor signaling to NF-kappaB; Dysregulated signal transduction in Diffuse Large B Cell Lymphoma; Regulation of NK Cell Maturation and Cytotoxicity; CRISPR/Cas9- based genetic screens in immunity and cancner.

Systems biology, computational medicine and biology, angiogenesis, cancer, immuno-oncology, peripheral arterial disease

Genes and Neural Circuits Required for Insect Olfaction

Mechanisms of Osmotic Regulation in Physiology and Disease

Ion transport in health and disease. Emerging roles for Ca2+ signaling and endosomal pH in cancer, autism and neurodegenerative disorders

Understanding how the nuclear periphery and other subcompartments contribute to general nuclear architecture and to specific gene regulation

Signaling Network Dynamics at Single Cell Level

Genome technology; Genome assembly; Gene finding; Bioinformatics; Genomics

Computational neuroscience, estimation and control theory, applications to disorders of the central nervous system and brain machine interfaces

Neuroglycobiology; Glycobiology; Cell-cell interactions in the nervous system; Cell-cell interactions in the control of inflammation

Mitochondrial Dynamics and Phospholipid Metabolism

Mechanisms of movement control in humans, learning control of the arm, brain imaging, robotics and adaptive control, computational neuroscience

Neural Mechanisms of Reward Dependent Learning

Medical imaging, image-guided surgery, interventional radiology, radiation therapy, 3D imaging, spectral imaging, CT, cone-beam CT, imaging physics, image quality, image registration

Mechanistic Control of Neuronal and Glial Differentiation and Function

Medical imaging, device design and optimization, adaptive imaging, task-based acquisition, reconstruction, and estimation theory

Research: Neurophysiological Mechanisms of Decision Making and Self-Control

Epigenetic pathways in disease, histone and chromatin modifications, and small RNA directed gene silencing

Medical instrumentation, neuroengineering, neural signal processing and clinical instrumentation, micro/nano scale sensors, devices and systems

Neurophysiology of the auditory cortex, neural mechanisms of speech perception and learning, computational neuroscience

HIV; Central nervous system drug delivery; Neuroimmunology; Substance abuse

Nuclear envelope, lamins and nucleoskeleton; Emery-Dreifuss muscular dystrophy

synthesis and preclinical validation of biomaterials-based immunomodulatory therapies that bias the adaptive immune response towards immunity or tolerance

Statistical modeling and analysis of cardiovascular gene and protein expression data, and computational modeling of signal transduction, mitochondrial energetics, ion channel function, and intracellular calcium dynamics in cardiac myocytes and vascular endothelial cells

Structural and molecular mechanisms of ubiquitin signaling and chromatin modification; regulation of transcription

Cellular and organismal metabolism 

Metabolic physiology of secreted hormones

Molecular Mechanisms of Neuronal Plasticity

Single-molecule and single-cell studies of cell division, chromosome conformation, transcription and gene regulation

Biotechnology and clinical aspects of carbohydrate engineering

Cellular and Molecular Neuroscience

Biophotonics; Volumetric and Multimodal Imaging; Fiber Optics and Endoscopy; Structural and Functional Relation in Biological Systems; Early Detection and Monitoring of Cancer and Other Chronic Diseases; Imaging Biomarkers

O-GlcNAc, A Novel Regulator of the Cellular Stress Response and Cell Survival

Medical imaging, modeling and evaluation of imaging systems, CT algorithms, quantitative CT and cone-beam CT, imaging biomarkers of bone and joint health, musculoskeletal radiology

Theoretical and computational neuroscience, neural computation