Organogenesis in a model system: Formation of the Drosophila salivary gland and trachea

Telomere and Telomerase-Associated Disorders

In-vivo biosensing, personalized drug therapy, molecular diagnostics

Molecular Mechanisms of Neuronal Plasticity

Mechanisms of Human Movement Disorders

Computational regulatory genomics

Molecular Basis of Neuronal and Glial Cell Fate Specification and Survival

Functional Organization of Local Circuits of the Neocortex

Drug Metabolism and preclinical drug development; small molecule mass spectrometry; targeted metabolomics; antiviral drug-induced toxicity; modulation of cellular signaling pathways by reactive metabolites.

Computational and experimental exploration of gene regulatory networks in development, stem cell engineering, tumorigenesis and cancer progression

TRP channel function in thermosensation, pain and inflammation

Data science, signal processing, machine learning, computational neuroscience, computational imaging, cybernetics

Computer vision, pattern recognition, machine learning, artificial intelligence, signal and image processing

Decision-making, neuroeconomics, neural control of movement, functional brain imaging, noninvasive brain stimulation

Molecular Pathogenesis and Latency of SIV & HIV

Transcriptional and Post-transcriptional Mechanisms for Cell Diversification

Neural Circuits for Reward, Mood, and Decision Making

Mass spectrometry strategies to characterize proteins and their modifications in malnutrition, neurological diseases and cancer

Object Synthesis in Higher Level Visual Cortex

Multisensory integration for action and perception, neural mechanisms of motor learning, neural prosthesis and rehabilitation, computational neuroscience

Cystic Fibrosis, Genetics, Medical Genetics

Hair cell regeneration; Hearing; Auditory development

Circuit and Synaptic Mechanisms of Social Cognition in Health and Disease

Immunoengineering, regenerative medicine, biomaterials/biomedical devices, controlled drug delivery, synthetic and systems biology, and automimmune, cancer, and infectious disease models

Molecular and Genetic Studies on Pain-Sensing Neurons

Cellular regulation of cholesterol homeostasis and adaptation to hypoxia

Mechanisms driving growth and development of normal epithelial cells; Cellular strategies driving cancer invasion and metastasis; Regulation of cancer progression by the tumor microenvironment

Epigenetics in development and disease

Neural Basis of Multisensory Perception and Decision Making

NMR studies of active enzymatic systems: dynamic molecular communication in Nonribosomal Peptide Synthetases

Zinc transporters: biochemistry, biophysics and cell biology

Mechanism and biology of small silencing RNAs

Cardiovascular disease; Cancer; Pathology; Toxicology; Signal transduction; Cancer therapy

Single Cell Variation in Neural Development and Disease

Organelle biogenesis; Peroxisome biogenesis; Virology; Exosome biology; Exosomes and microvesicles (EMVs); Human immunodeficiency virus (HIV)

Engineering functional craniofacial and orthopaedic constructs for use in therapeutic applications

Mechanisms of Ribosome Translation and Translational Control

Genetic disorders associated with defective fluid and electrolyte movement; ion channel and epithelial transport physiology

Single-Molecule Studies of Genomic Maintenance

Infectious Disease Modeling; Evolutionary Dynamics; Viral Dynamics; HIV/AIDS; Drug Resistance

Molecular mechanisms underlying accurate chromosome segregation and centrosome duplication

Regulation of Neurotransmitter Receptors and Brain Function in Health and Disease

Lipid Signaling in Chemotaxis

Synthetic cell biology: total synthesis of cellular functions such as neutrophil chemotaxis and ciliary mechano-sensation

Systems neuroscience, brain development, in vivo imaging, neuroengineering, neurophysiology

Neurophysiology of Memory in the Hippocampal Formation

Regulatory pathways that control adaptive metabolic responses in adipose and skeletal muscle tissues

Mechanism of biological force generation, laser-induced optical forces

Mechanisms of Brain Cancer Stem Cell Regulation

Receptor-ligand interactions and conformational transitions using computational and experimental approaches

Cellular/Molecular Mechanisms of Synaptic Plasticity Underlying Memory Formation and Cross-Modal Plasticity

Medical imaging and biophotonics

Neuronal Plasticity, Broadly Considered

Theoretical Modeling, Mechanobiology, Cell Migration, Membrane Trafficking, Cell Division

Proteomics; Animal models for Wilson disease, Menkes disease; Redox biology; Metal biology (copper, iron, zinc); Ion transport; Membrane proteins biochemistry; trafficking assembly regulation

Computational modeling of growth factor-receptor networks, personalized medicine, therapeutic cardiovascular remodeling, novel methods for data visualization and automated image analysis

Genetics basis of congenital malformations; Genetics of neurological, neuropsychiatric and neural-crest disorders; Transcriptional regulation in development and disease

The Regulation of Neuronal Gene Expression in Health and Disease

Progeria and lamin A processing by the ZMPSTE24 protease; ERAD and cytosolic protein quality control; yeast and mammalian cell biology

Data science, computational neuroscience, medical imaging, computational anatomy, pattern theory

Auditory Perception and Development of Neocortical Circuits

Molecular mechanisms of retinal development and disease; the role of Frizzled receptors in mammalian development

Computational Neuroscience

Neural Circuits Underlying Object Recognition

Molecular dissection of host-pathogen interactions and the evolution of virulence strategies in natural reservoirs

Sequence motif finding; Splice site prediction; Computational gene finding

Elucidating the role of sensory receptors, such as olfactory receptors, in regulating renal function

Mechanisms of signal transduction in immunity and cancer; antigen receptor signaling to NF-kappaB; Dysregulated signal transduction in Diffuse Large B Cell Lymphoma; Regulation of NK Cell Maturation and Cytotoxicity; CRISPR/Cas9- based genetic screens in immunity and cancner.

Genes and Neural Circuits Required for Insect Olfaction

Mechanisms of Osmotic Regulation in Physiology and Disease

Physiological functions of DGKs in neurons; Enzyme structure/function studies; Interfacial enzymology of lipid metabolizing signaling enzymes

Ion transport in health and disease. Emerging roles for Ca2+ signaling and endosomal pH in cancer, autism and neurodegenerative disorders

Down syndrome, animal models to clinical trials

Signaling Network Dynamics at Single Cell Level

Genome technology; Genome assembly; Gene finding; Bioinformatics; Genomics

Computational neuroscience, estimation and control theory, applications to disorders of the central nervous system and brain machine interfaces

Neuroglycobiology; Glycobiology; Cell-cell interactions in the nervous system; Cell-cell interactions in the control of inflammation

Mitochondrial Dynamics and Phospholipid Metabolism

Mechanisms of movement control in humans, learning control of the arm, brain imaging, robotics and adaptive control, computational neuroscience

Neural Mechanisms of Reward Dependent Learning

Medical imaging, image-guided surgery, interventional radiology, radiation therapy, 3D imaging, spectral imaging, CT, cone-beam CT, imaging physics, image quality, image registration

Mechanistic Control of Neuronal and Glial Differentiation and Function

Medical imaging, device design and optimization, adaptive imaging, task-based acquisition, reconstruction, and estimation theory

Research: Neurophysiological Mechanisms of Decision Making and Self-Control

Epigenetic pathways in disease, histone and chromatin modifications, and small RNA directed gene silencing

Medical instrumentation, neuroengineering, neural signal processing and clinical instrumentation, micro/nano scale sensors, devices and systems

Cellular and molecular characterizations of rapid changes during synaptic plasticity

HIV; Central nervous system drug delivery; Neuroimmunology; Substance abuse

Nuclear envelope, lamins and nucleoskeleton; Emery-Dreifuss muscular dystrophy

synthesis and preclinical validation of biomaterials-based immunomodulatory therapies that bias the adaptive immune response towards immunity or tolerance

Structural and molecular mechanisms of ubiquitin signaling and chromatin modification; regulation of transcription

Cellular and organismal metabolism 

Metabolic physiology of secreted hormones

Single molecule imaging, RNA biology, neuroscience and gene expression

Single-molecule and single-cell studies of cell division, chromosome conformation, transcription and gene regulation

Biotechnology and clinical aspects of carbohydrate engineering

Innovation and design of healthcare solutions

Biophotonics; Volumetric and Multimodal Imaging; Fiber Optics and Endoscopy; Structural and Functional Relation in Biological Systems; Early Detection and Monitoring of Cancer and Other Chronic Diseases; Imaging Biomarkers

O-GlcNAc, A Novel Regulator of the Cellular Stress Response and Cell Survival

Medical imaging, modeling and evaluation of imaging systems, CT algorithms, quantitative CT and cone-beam CT, imaging biomarkers of bone and joint health, musculoskeletal radiology

Systems biology, construction of networks and pathways, transcription regulation, and pathogen-host interactions.